Pub. Date : 2014 Jun
PMID : 24710315
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects: an isobologram analysis. | Dizocilpine Maleate | carbonic anhydrase 1 | Rattus norvegicus |
| 2 | This study investigated the possible involvement of the CA1 GABAA receptors in anxiolytic-like effects induced by (+)-MK-801 (a noncompetitive antagonist of the NMDA subtype of the glutamate receptor). | Dizocilpine Maleate | carbonic anhydrase 1 | Rattus norvegicus |
| 3 | An intra-CA1 injection of (+)-MK-801 (2 mug/rat) and muscimol (0.5 mug/rat; a GABAA receptor agonist) increased %OAT and %OAE by themselves while not altering the closed arm entries, indicating an anxiolytic-like effect of these drugs. | Dizocilpine Maleate | carbonic anhydrase 1 | Rattus norvegicus |
| 4 | In conclusion, the CA1 GABAA receptors appear to be involved in anxiolytic-like behaviors induced by (+)-MK-801. | Dizocilpine Maleate | carbonic anhydrase 1 | Rattus norvegicus |