Title : Halofuginone improves muscle-cell survival in muscular dystrophies.

Pub. Date : 2014 Jul

PMID : 24703880






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Halofuginone treatment of mdx mice reduced the apoptotic nuclei number in the diaphragm, together with reduction in Bax and induction in Bcl2 levels in myofibers isolated from these mice. halofuginone BCL2-associated X protein Mus musculus
2 Inhibition of apoptosis or staurosporine-induced apoptosis by halofuginone in mdx primary myoblasts and C2 myogenic cell line, respectively, was reflected by less pyknotic/apoptotic cells and reduced Bax expression. halofuginone BCL2-associated X protein Mus musculus