Pub. Date : 2014 Jul
PMID : 24699373
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In Saccharomyces cerevisiae, leucine uptake is mediated by multiple amino acid permeases, including the high-affinity leucine permease Bap2. | Leucine | branched-chain amino acid permease BAP2 | Saccharomyces cerevisiae S288C |
| 2 | Upon leucine binding, these alpha-helix breaks were assumed to mediate a conformational transition in Bap2 from an outward-open to a substrate-binding occluded state. | Leucine | branched-chain amino acid permease BAP2 | Saccharomyces cerevisiae S288C |
| 3 | Bap2-mediated leucine import was inhibited by some amino acids according to the following order of severity: phenylalanine, leucine>isoleucine>methionine, tyrosine>valine>tryptophan; histidine and asparagine had no effect. | Leucine | branched-chain amino acid permease BAP2 | Saccharomyces cerevisiae S288C |
| 4 | Bap2-mediated leucine import was inhibited by some amino acids according to the following order of severity: phenylalanine, leucine>isoleucine>methionine, tyrosine>valine>tryptophan; histidine and asparagine had no effect. | Leucine | branched-chain amino acid permease BAP2 | Saccharomyces cerevisiae S288C |