Title : [Regulation of aquaporin 3 protein expression in amnion epithelial cells through cAMP-PKA signal pathway].

Pub. Date : 2014 Jan

PMID : 24694916






3 Functional Relationships(s)
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1 (3) After different concentration of forskolin treated 2 hours, the expression of total CREB had no significant difference among them(P > 0.05). Colforsin cAMP responsive element binding protein 1 Homo sapiens
2 While the expression of cAMP level, PKA activity, p-CREB and AQP3 protein were significantly changed, which were higher in 2.5 micromol/L, 5 micromol/L, 50 micromol/L forskolin group when compared with 0 micromol/L (P < 0.05). Colforsin cAMP responsive element binding protein 1 Homo sapiens
3 (6) p-CREB and AQP3 protein expression were significantly lower in 5 micromol/L forskolin combined 10 micromol/L H-89 incubating 2 hours group when compared with 5 micromol/L forskolin, but higher than that in 10 micromol/L H-89 treated group (P < 0.05). Colforsin cAMP responsive element binding protein 1 Homo sapiens