Title : Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1.

Pub. Date : 2014 Jun 20

PMID : 24689980






1 Functional Relationships(s)
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1 Furthermore, we show that stress-independent HSF1 activation decreases intracellular aggregation of a model polyglutamine-containing protein and reduces the cellular toxicity of environmental toxins like arsenite that disrupt cytosolic proteostasis. polyglutamine heat shock transcription factor 1 Homo sapiens