Title : The de-ubiquitinating enzyme ataxin-3 does not modulate disease progression in a knock-in mouse model of Huntington disease.

Pub. Date : 2013

PMID : 24683430






1 Functional Relationships(s)
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1 Ataxin-3 is a deubiquitinating enzyme (DUB) that participates in ubiquitin-dependent protein quality control pathways and, based on studies in model systems, may be neuroprotective against toxic polyglutamine proteins such as the Huntington"s disease (HD) protein, huntingtin (htt). polyglutamine ataxin 3 Mus musculus