Title : Hybrid molecules inhibiting myeloperoxidase activity and serotonin reuptake: a possible new approach of major depressive disorders with inflammatory syndrome.

Pub. Date : 2014 Aug

PMID : 24673477






1 Functional Relationships(s)
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1 KEY FINDINGS: 3-(aminoalkyl)-5-fluoroindole derivative with 5 carbons on the side chain and paroxetine showed the best activity on both MPO and SERT at the nanomolar range. Carbon myeloperoxidase Homo sapiens