Title : Effects of serotonin-active drugs on prolactin secretion in male rats.

Pub. Date : 1988 Jan-Feb

PMID : 2467272






5 Functional Relationships(s)
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1 Effects of serotonin-active drugs on prolactin secretion in male rats. Serotonin prolactin Rattus norvegicus
2 The effects of several serotonin acting drugs on serum prolactin levels were studied in male rats. Serotonin prolactin Rattus norvegicus
3 Administration of the serotonin precursor, 5-hydroxytryptophan (5-HTP; 250 mg/kg ip) or pargyline (5 mg/kg ip) with 5-HTP (100 mg/kg ip) significantly increased serum prolactin concentration. Serotonin prolactin Rattus norvegicus
4 Depletion of serotonin stores by pretreatment with p-chloro-phenylalanine methyl-ester (PCPA; 3 x 300 mg/kg ip) significantly prevent the effect of quipazine on prolactin levels. Serotonin prolactin Rattus norvegicus
5 Serotonin uptake blocker, fluoxetine (10 mg/kg ip) produces an increase in the prolactin concentrations of the serum. Serotonin prolactin Rattus norvegicus