Title : Curcumin and vitamin E protect against adverse effects of benzo[a]pyrene in lung epithelial cells.

Pub. Date : 2014

PMID : 24664296






2 Functional Relationships(s)
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1 The ratio of Bax/Bcl-2 was also significantly increased in cells exposed to BaP and this increase was reversed by VE co-treatment. Benzo(a)pyrene BCL2 associated X, apoptosis regulator Homo sapiens
2 Taken together, BaP-induced cytotoxicity occurs through DNA damage, cell cycle arrest, ROS production, modulation of metabolizing enzymes, and the expression/activation of p53, PARP-1, survivin, and Bax/Bcl-2. Benzo(a)pyrene BCL2 associated X, apoptosis regulator Homo sapiens