Title : Effect of murine gamma interferon on the cellular responses to bleomycin in mice.

Pub. Date : 1988

PMID : 2465144






3 Functional Relationships(s)
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1 Effect of murine gamma interferon on the cellular responses to bleomycin in mice. Bleomycin interferon gamma Mus musculus
2 Because in vitro studies have shown inhibition of fibroblast proliferation and collagen synthesis by interferon, we tested the hypothesis that murine gamma interferon inhibits bleomycin-induced pulmonary fibrosis in mice. Bleomycin interferon gamma Mus musculus
3 These results suggest an inhibitory action of gamma interferon on collagen accumulation and fibroblast proliferation associated with lymphocyte accumulation in the lungs of mice following bleomycin administration. Bleomycin interferon gamma Mus musculus