Title : Antagonists of luteinizing hormone releasing hormone bind to rat mast cells and induce histamine release.

Pub. Date : 1988 Dec

PMID : 2464275






4 Functional Relationships(s)
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1 Antagonists of luteinizing hormone releasing hormone bind to rat mast cells and induce histamine release. Histamine gonadotropin releasing hormone 1 Rattus norvegicus
2 We conclude that histamine release from rat mast cells induced by LHRH analogs is mediated by specific binding of the active peptides to cell membranes. Histamine gonadotropin releasing hormone 1 Rattus norvegicus
3 Furthermore, using rat mast cells, the binding assay in conjunction with histamine releasing assay may be utilized to predict the in vivo histamine releasing potential of new LHRH peptides which are of clinical importance. Histamine gonadotropin releasing hormone 1 Rattus norvegicus
4 Furthermore, using rat mast cells, the binding assay in conjunction with histamine releasing assay may be utilized to predict the in vivo histamine releasing potential of new LHRH peptides which are of clinical importance. Histamine gonadotropin releasing hormone 1 Rattus norvegicus