Title : Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence.

Pub. Date : 2013

PMID : 24642724






2 Functional Relationships(s)
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1 Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence. 25-hydroxyvitamin D 7-dehydrocholesterol reductase Homo sapiens
2 BACKGROUND/AIMS: Recent genome-wide association studies have identified the rs1790349 and rs12785878 single-nucleotide polymorphisms (SNPs), present in the NADSYN1/DHCR7 locus, as an influential player on circulating 25-hydroxyvitamin D [25(OH)D] levels, which itself has been linked to various diseases including cardiovascular disease (CVD). 25-hydroxyvitamin D 7-dehydrocholesterol reductase Homo sapiens