Title : NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells.

Pub. Date : 2014

PMID : 24642534






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inside the cells 1,25D is degraded to calcitrioic acid by a mitochondrial enzyme CYP24A1, while ATRA is degraded to several polar metabolites by CYP26. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens