Title : Cellular and clinical pharmacology of the taxanes docetaxel and paclitaxel--a review.

Pub. Date : 2014 May

PMID : 24637579






1 Functional Relationships(s)
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1 The metabolism of paclitaxel is mediated primarily by the P450 cytochrome enzymes CYP2C8 and CYP3A, whereas docetaxel is only metabolized by CYP3A4. Paclitaxel cytochrome P450 family 3 subfamily A member 4 Homo sapiens