Title : All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway.

Pub. Date : 2014 Apr

PMID : 24635079






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ATRA also induced G1 cell-cycle arrest, inhibited the expression of cyclin D1/cyclin-dependent kinase (CDK)4 and cyclinE/CDK2, and increased the expression of the cyclin-dependent kinase inhibitors p21 and p27. Tretinoin cyclin D1 Homo sapiens