Title : Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate.

Pub. Date : 2014 Mar

PMID : 24598914






1 Functional Relationships(s)
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1 Crystal structures of hFPPS in ternary complexes with a novel bisphosphonate, YS0470, and the secondary ligands inorganic phosphate (Pi), inorganic pyrophosphate (PPi) and isopentenyl pyrophosphate (IPP) have recently been reported. Diphosphonates farnesyl diphosphate synthase Homo sapiens