Title : Association between reduced folate carrier G80A polymorphism and methotrexate toxicity in childhood acute lymphoblastic leukemia: a meta-analysis.

Pub. Date : 2014 Dec

PMID : 24597986






1 Functional Relationships(s)
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1 Abstract Methotrexate (MTX) is a key component of chemotherapeutic regimens for childhood acute lymphoblastic leukemia (ALL), and enters the cell via active transport mediated by the reduced folate carrier (RFC1). Folic Acid replication factor C subunit 1 Homo sapiens