Title : β-Arrestin-2 knockout prevents development of cellular μ-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons.

Pub. Date : 2015 Jan

PMID : 24597632






1 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: Tolerance to the behavioural effects of morphine is blunted in beta-arrestin-2 knockout mice, but opioid withdrawal is largely unaffected. Morphine arrestin, beta 2 Mus musculus