Title : Insulin antagonism of catecholamine stimulation of fatty acid transport in the adipocyte. Studies on its mechanism of action.

Pub. Date : 1988 Oct 15

PMID : 2459120






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Insulin was effective in antagonizing the effect of cAMP analogs which were good substrates for the phosphodiesterase and failed to suppress the effect of those which were poorly hydrolyzed by the enzyme. Cyclic AMP insulin Homo sapiens
2 Also consistent with involvement of cAMP lowering in insulin action was the finding that adenosine removal greatly diminished insulin"s responsiveness. Cyclic AMP insulin Homo sapiens
3 In conclusion, our studies support the involvement of cAMP lowering in insulin"s antagonism of fatty acid transport stimulation in the adipocyte. Cyclic AMP insulin Homo sapiens