Title : Differences in c-Jun N-terminal kinase recognition and phosphorylation of closely related stathmin-family members.

Pub. Date : 2014 Mar 28

PMID : 24589734






2 Functional Relationships(s)
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1 Previously, we characterized mechanisms underlying JNK phosphorylation of STMN at proline-flanked serine residues (Ser25 and Ser38) that are conserved across STMN-like proteins. Serine mitogen-activated protein kinase 8 Homo sapiens
2 In this study, we demonstrated using in vitro kinase assays and alanine replacement of serine residues that JNK phosphorylated the STMN-like domain (SLD) of SCG10 on Ser73, consistent with our previous finding that STMN Ser38 was the primary JNK target site. Serine mitogen-activated protein kinase 8 Homo sapiens