Pub. Date : 2014 May
PMID : 24584843
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Farnesol induces apoptosis of DU145 prostate cancer cells through the PI3K/Akt and MAPK pathways. | Farnesol | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Farnesol increased the expression of p53, p-c-Jun N-terminal kinase, cleaved-caspase-3, Bax, and cleaved-caspase-9, but decreased the expression of p-phosphatidylinositol-3-kinase (PI3K), p-Akt, p-p38, Bcl-2, and p-extracellular signal-regulated protein kinase, in a dose-dependent manner. | Farnesol | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | The results indicated that farnesol induced apoptosis of DU145 prostate cancer cells through the PI3K/Akt and mitogen-activated protein kinase signaling pathways. | Farnesol | AKT serine/threonine kinase 1 | Homo sapiens |