Title : An altered spinal serotonergic system contributes to increased thermal nociception in an animal model of depression.

Pub. Date : 2014 Jun

PMID : 24584836






1 Functional Relationships(s)
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1 Autoradiographic studies demonstrated down-regulation of 5-HT transporters ([(3)H]citalopram binding) and decreased functionality of 5-HT1A receptors (8-OH-DPAT-stimulated [(35)S]GTPgammaS binding) in the dorsal horn of the lumbar spinal cord in OB rats. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Rattus norvegicus