Pub. Date : 2014 May
PMID : 24576481
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interestingly, the intrathecal introduction of inhibitors MAPKs and NF-kappaB into control mice decreased the lethality after 3-NP intoxication. | 3-nitropropionic acid | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Our findings indicate that EP may effectively alleviate 3-NP-induced striatal toxicity by inhibition of the MAPKs and NF-kappaB pathways in the striatum, and that EP has a wide therapeutic window, suggesting that EP may have therapeutic value in the treatment of aspects of HD"s disease related to inflammation. | 3-nitropropionic acid | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |