Title : Bufalin inhibited the growth of human osteosarcoma MG-63 cells via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway.

Pub. Date : 2014 May

PMID : 24570183






2 Functional Relationships(s)
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1 Bufalin inhibited the growth of human osteosarcoma MG-63 cells via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway. bufalin BCL2 apoptosis regulator Homo sapiens
2 By western blot analysis, we found that the up-regulation of Apaf-1, cleaved PARP, cleaved caspase-3, cleaved caspase-9, and Bax/Bcl-2, varies with different concentration of Bufalin. bufalin BCL2 apoptosis regulator Homo sapiens