Pub. Date : 2014 Mar 28
PMID : 24565839
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53 down-regulates SETDB1 gene expression during paclitaxel induced-cell death. | Paclitaxel | tumor protein p53 | Homo sapiens |
| 2 | PTX treatment induces the p53 protein, but down-regulates expression of SETDB1 at the transcriptional level as well as the protein level. | Paclitaxel | tumor protein p53 | Homo sapiens |
| 3 | This result demonstrates that PTX down-regulates SETDB1 gene expression in a p53 dependent manner, and p53 might participate in heterochromatic repression on the promoter regions of SETDB1. | Paclitaxel | tumor protein p53 | Homo sapiens |