Pub. Date : 2014 Jun
PMID : 24563318
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lithium chloride inhibits TGF-beta1-induced myofibroblast transdifferentiation via PI3K/Akt pathway in cultured fibroblasts from Tenon"s capsule of the human eye. | Lithium Chloride | transforming growth factor beta 1 | Homo sapiens |
| 2 | LiCl treatment reduced expression of TGF-beta1-induced alpha-SMA expression in HTFs. | Lithium Chloride | transforming growth factor beta 1 | Homo sapiens |
| 3 | LiCl also decreased Akt phosphorylation induced by TGF-beta1. | Lithium Chloride | transforming growth factor beta 1 | Homo sapiens |
| 4 | Thus, LiCl induces the suppression of transdifferentiation stimulated by TGF-beta1 by the regulation of PI3K/Akt signaling in HTFs. | Lithium Chloride | transforming growth factor beta 1 | Homo sapiens |