Pub. Date : 2014 Mar-Apr
PMID : 24561310
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, the effect of niclosamide, a Food and Drug Administration-approved antihelminthic drug, on the activation of lipopolysaccharide (LPS)-stimulated murine bone marrow-derived DCs was examined. | Niclosamide | toll-like receptor 4 | Mus musculus |
| 2 | Our experimental results show that niclosamide reduced the pro-inflammatory cytokine and chemokine expression of LPS-activated DCs. | Niclosamide | toll-like receptor 4 | Mus musculus |
| 3 | Blocking the LPS-induced activation of MAPK-ERK, JNK and NF-kappaB may contribute to the inhibitory effect of niclosamide on DC activation. | Niclosamide | toll-like receptor 4 | Mus musculus |