Title : OGlcNAcylation and phosphorylation have opposing structural effects in tau: phosphothreonine induces particular conformational order.

Pub. Date : 2014 Mar 12

PMID : 24559475






1 Functional Relationships(s)
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1 A series of peptides derived from the proline-rich domain (residues 174-251) of tau was synthesized, with free Ser/Thr hydroxyls, phosphorylated Ser/Thr (pSer/pThr), OGlcNAcylated Ser/Thr, and diethylphosphorylated Ser/Thr. Proline microtubule associated protein tau Homo sapiens