Title : Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway.

Pub. Date : 2014

PMID : 24551210






1 Functional Relationships(s)
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1 Blocking ER stress using 4-phenylbutyric acid not only down-regulated AMP-induced GRP78 and CHOP expression, but also significantly decreased AMP-induced cell growth inhibition and apoptosis, whereas ER stress inducer thapsigargin played opposing effects. 4-phenylbutyric acid DNA damage inducible transcript 3 Homo sapiens