Title : Gentian violet induces wtp53 transactivation in cancer cells.

Pub. Date : 2014 Apr

PMID : 24535435






3 Functional Relationships(s)
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1 In this study, we examined the effect of GV on wild-type (wt) p53 activity in cancer cells. Gentian Violet tumor protein p53 Homo sapiens
2 We found that GV was able to overcome the inhibitory effect of the NADPH oxidase Nox1 on p53 transcriptional activity. Gentian Violet tumor protein p53 Homo sapiens
3 For the first time we show that GV was able to directly induce p53/DNA binding and transcriptional activity. Gentian Violet tumor protein p53 Homo sapiens