Title : Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling.

Pub. Date : 2014 Apr

PMID : 24535192






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Exposure of cells to arsenite for 24 h rendered cells less responsive toward stimulation of Akt by insulin. arsenite AKT serine/threonine kinase 1 Homo sapiens
2 At the same time, short-term exposure to arsenite induced a concentration-dependent increase in phosphorylation of Akt at Ser-473, followed by phosphorylation of FoxO proteins at sites known to be phosphorylated by Akt. arsenite AKT serine/threonine kinase 1 Homo sapiens
3 At the same time, short-term exposure to arsenite induced a concentration-dependent increase in phosphorylation of Akt at Ser-473, followed by phosphorylation of FoxO proteins at sites known to be phosphorylated by Akt. arsenite AKT serine/threonine kinase 1 Homo sapiens