Title : Evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease.

Pub. Date : 2014 Jul

PMID : 24534762






2 Functional Relationships(s)
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1 Intermediate-length polyQ expansions (>24 Qs) of ATXN2 were found in 7 ADPD patients and no controls (7/299 = 2.34% and 0/329 = 0%, respectively; p = 0.0053 < 0.05/8 after Bonferroni correction). polyglutamine ataxin 2 Homo sapiens
2 Our results may support the hypothesis that ATXN2 polyQ expansion is a specific predisposing factor for multiple neurodegenerative diseases. polyglutamine ataxin 2 Homo sapiens