Title : Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.

Pub. Date : 2014 Apr

PMID : 24534704






4 Functional Relationships(s)
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1 Oxidation of LDL by the myeloperoxidase (MPO)-H2O2-chloride system is a key event in the development of atherosclerosis. Chlorides myeloperoxidase Homo sapiens
2 Oxidation of LDL by the myeloperoxidase (MPO)-H2O2-chloride system is a key event in the development of atherosclerosis. Chlorides myeloperoxidase Homo sapiens
3 Using MS, we further analyzed in vitro modifications of apoB-100 by hypochlorous acid (HOCl) generated by the MPO-H2O2-chloride system or added as a reagent. Chlorides myeloperoxidase Homo sapiens
4 Furthermore, differences were observed between LDL oxidized by reagent HOCl or HOCl generated by the MPO-H2O2-chloride system. Chlorides myeloperoxidase Homo sapiens