Title : Effect of azithromycin on Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages.

Pub. Date : 2014 Apr 15

PMID : 24534490






2 Functional Relationships(s)
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1 In addition, azithromycin up-regulated the mRNA level of SOCS1 in cells treated with LPS. Azithromycin suppressor of cytokine signaling 1 Mus musculus
2 In conclusion, azithromycin significantly attenuated P. intermedia LPS-induced production of IL-6 in murine macrophages via inhibition of NF-kappaB, STAT1 and STAT3 activation, which is possibly related to the activation of SOCS1 signaling. Azithromycin suppressor of cytokine signaling 1 Mus musculus