Title : Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review.

Pub. Date : 2014

PMID : 24533814






1 Functional Relationships(s)
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1 However, most known inducers (e.g., triterpenoids, isothiocyanates and sulfoxythiocarbamates) that activate the ARE system through electrophilic attacks on the cysteine sulfhydryl group of Keap1 also disrupt theKeap1-Nrf2 interaction. Isothiocyanates NFE2 like bZIP transcription factor 2 Homo sapiens