Title : Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells.

Pub. Date : 2014

PMID : 24520215






2 Functional Relationships(s)
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Protein Name
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1 Cerulenin inhibited MCF-7-MEK5 cell migration and EMT, and reduced FASN expression and down-stream proteins L-FABP, VEGF, and VEGFR-2. Cerulenin fatty acid synthase Homo sapiens
2 Immunohistochemistry further showed that increased percentage of FASN-positive cells in the tumor tissue was associated with increased percentages of L-FABP- and VEGF-positive cells and the Cerulenin treatment could reverse the effect. Cerulenin fatty acid synthase Homo sapiens