Title : Specific phosphorylation of 22-kD proteins by various inducers for granuloid differentiation in myeloid leukemic cells.

Pub. Date : 1988

PMID : 2451772






2 Functional Relationships(s)
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1 The phosphorylation of 22 kD, pI 6.0 and 5.8 proteins (pp22) in HL-60 cells or myeloid leukemic cells from patients, was enhanced by treatment with granuloid inducers such as retinoic acid, dimethyl sulfoxide or G-CSF, in common with prostaglandin E2 and theophylline, or dibutyryl c-AMP, which increased intracellular c-AMP. Tretinoin cathelicidin antimicrobial peptide Homo sapiens
2 The phosphorylation of 22 kD, pI 6.0 and 5.8 proteins (pp22) in HL-60 cells or myeloid leukemic cells from patients, was enhanced by treatment with granuloid inducers such as retinoic acid, dimethyl sulfoxide or G-CSF, in common with prostaglandin E2 and theophylline, or dibutyryl c-AMP, which increased intracellular c-AMP. Tretinoin cathelicidin antimicrobial peptide Homo sapiens