Title : Mycophenolic acid mediated disruption of the intestinal epithelial tight junctions.

Pub. Date : 2014 Apr 1

PMID : 24509232






2 Functional Relationships(s)
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1 Additionally ML-7, a specific inhibitor of MLCK was able to reverse both the MPA mediated decrease in TER and the increase in FITC-dextran influx, suggesting a modulating role of MPA on epithelial barrier permeability via MLCK activity. fluorescein isothiocyanate dextran myosin light chain kinase Homo sapiens
2 Additionally ML-7, a specific inhibitor of MLCK was able to reverse both the MPA mediated decrease in TER and the increase in FITC-dextran influx, suggesting a modulating role of MPA on epithelial barrier permeability via MLCK activity. fluorescein isothiocyanate dextran myosin light chain kinase Homo sapiens