Title : Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.

Pub. Date : 2014 Apr 15

PMID : 24508728






3 Functional Relationships(s)
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1 CTGF reporter mice demonstrated increased CTGF promoter activity by lung epithelial cells acutely after bleomycin in vivo. Bleomycin cellular communication network factor 2 Mus musculus
2 CTGF reporter mice demonstrated increased CTGF promoter activity by lung epithelial cells acutely after bleomycin in vivo. Bleomycin cellular communication network factor 2 Mus musculus
3 Furthermore, mice with lung epithelial cell-specific deletion of CTGF had an attenuated fibrotic response to bleomycin. Bleomycin cellular communication network factor 2 Mus musculus