Title : Mild lipid stress induces profound loss of MC4R protein abundance and function.

Pub. Date : 2014 Mar

PMID : 24506538






1 Functional Relationships(s)
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1 The loss of cAMP signaling in response to alpha-MSH by elevated palmitate was corrected by treatment with a chemical chaperone, 4-phenylbutyrate in both mHypoE-42 hypothalamic neurons and in Neuro2A cells in which protein abundance of HA-MC4R-GFP was increased. 4-phenylbutyric acid pro-opiomelanocortin-alpha Mus musculus