Title : Excitotoxic glutamate insults block autophagic flux in hippocampal neurons.

Pub. Date : 2014 Jan 13

PMID : 24505621






1 Functional Relationships(s)
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1 Additionally, while the autophagy inhibitor chloroquine had no effect, significant neuroprotection was seen instead with two drugs that enhance autophagy induction by different mechanisms, rapamycin (mTOR-dependent) and trehalose (mTOR-independent). Trehalose mechanistic target of rapamycin kinase Homo sapiens