Title : Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.

Pub. Date : 2014 Apr 3

PMID : 24501217






2 Functional Relationships(s)
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1 We found decreased transcription of the Rac guanine nucleotide exchange factors Tiam1 and Vav1 in unstimulated peripheral blood CLL cells with almost complete loss of Tiam1 but increased transcription of the potential Rac antagonist RhoH. Guanine Nucleotides AKT serine/threonine kinase 1 Homo sapiens
2 We found decreased transcription of the Rac guanine nucleotide exchange factors Tiam1 and Vav1 in unstimulated peripheral blood CLL cells with almost complete loss of Tiam1 but increased transcription of the potential Rac antagonist RhoH. Guanine Nucleotides AKT serine/threonine kinase 1 Homo sapiens