Title : In vitro osteogenic induction of bone marrow stromal cells with encapsulated gene-modified bone marrow stromal cells and in vivo implantation for orbital bone repair.

Pub. Date : 2014 Jul

PMID : 24498882






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1 In conclusion, encapsulation of genetically modified BMSCs was able to release a sufficient amount of BMP-2 and VEGF, which effectively induced osteogenic differentiation of normal-cultured BMSCs and demonstrated bone repair of the orbital wall defect after implantation with beta-TCP in vivo. beta-tricalcium phosphate bone morphogenetic protein 2 Canis lupus familiaris