Pub. Date : 2014
PMID : 24498418
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with ethyl pyruvate ameliorated the pathological effects of Con A-induced autoimmune hepatitis and significantly decreased the levels of TNF-alpha, IL-2, IL-6 and IL-1beta at 3h and 6h and the level of HMGB1 at 6h and 24h post injection. | ethyl pyruvate | high mobility group box 1 | Mus musculus |
| 2 | CONCLUSION: Taken together, these results indicated that ethyl pyruvate protected against Con A-induced autoimmune hepatitis by decreasing both early (TNF-alpha, IL-2, IL-1beta and IL-6) and late (HMGB1) cytokine expression in mice. | ethyl pyruvate | high mobility group box 1 | Mus musculus |