Title : Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy.

Pub. Date : 2014 Sep

PMID : 24496315






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this model, HES coadministration with Alternaria/OVA suppressed early IL-33 release, innate lymphoid cell (ILC) production of IL-4, IL-5, and IL-13, and localized eosinophilia. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
2 Upon OVA challenge, type 2 ILC (ILC2)/Th2 cytokine production and eosinophilia were diminished in HES-treated mice. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
3 Administration of recombinant IL-33 at sensitization with Alternaria/OVA/HES abrogated HES suppression of OVA-specific responses at challenge, indicating that suppression of early Alternaria-induced IL-33 release could be central to the anti-allergic effects of HES. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
4 Administration of recombinant IL-33 at sensitization with Alternaria/OVA/HES abrogated HES suppression of OVA-specific responses at challenge, indicating that suppression of early Alternaria-induced IL-33 release could be central to the anti-allergic effects of HES. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
5 Administration of recombinant IL-33 at sensitization with Alternaria/OVA/HES abrogated HES suppression of OVA-specific responses at challenge, indicating that suppression of early Alternaria-induced IL-33 release could be central to the anti-allergic effects of HES. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
6 Administration of recombinant IL-33 at sensitization with Alternaria/OVA/HES abrogated HES suppression of OVA-specific responses at challenge, indicating that suppression of early Alternaria-induced IL-33 release could be central to the anti-allergic effects of HES. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus
7 Administration of recombinant IL-33 at sensitization with Alternaria/OVA/HES abrogated HES suppression of OVA-specific responses at challenge, indicating that suppression of early Alternaria-induced IL-33 release could be central to the anti-allergic effects of HES. Helium serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus