Title : PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation: a comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells.

Pub. Date : 2006

PMID : 24489530






1 Functional Relationships(s)
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1 Rosiglitazone and pioglitazone (10 muM) increased pentose synthesis from [U-13C18]stearate by 127% and 185%, respectively, while PNU-91325 rather increased glutamate synthesis in the Krebs cycle by 113% as compared to control vehicle treated cells. Pioglitazone latexin Homo sapiens