Title : Anti-inflammatory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone via NF-κB inactivation in lipopolysaccharide-stimulated RAW 264.7 macrophage.

Pub. Date : 2014 Apr

PMID : 24481726






1 Functional Relationships(s)
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1 In particular, 5HHMF significantly inhibited the LPS-induced nuclear factor-kappaB (NF-kappaB) translocation from the cytosol to the nucleus, which was associated with the abrogation of inhibitory IkappaBalpha degradation and subsequent decreases in nuclear p65 levels. 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus