Title : PGE2 production is suppressed by chemically-synthesized Δ7-eicosatrienoic acid in macrophages through the competitive inhibition of COX-2.

Pub. Date : 2014 Apr

PMID : 24480038






1 Functional Relationships(s)
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1 Furthermore, PGE2 production reduced by Delta7-ETrA was highly correlated with the extent of Delta7-ETrA incorporation into cellular phospholipids and appeared to be the result of competition between this unusual fatty acid and arachidonic acid (AA) for COX-2. Arachidonic Acid cytochrome c oxidase II, mitochondrial Mus musculus