Title : [Design, synthesis and evaluation of bis-nicotine derivatives as inhibitors of cholinesterases and beta-amyloid aggregation].

Pub. Date : 2013 Nov

PMID : 24475704






1 Functional Relationships(s)
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1 A Lineweaver-Burk plot and molecular modeling study showed that these derivatives targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens