Title : Phase Ib study of Buparlisib plus Trastuzumab in patients with HER2-positive advanced or metastatic breast cancer that has progressed on Trastuzumab-based therapy.

Pub. Date : 2014 Apr 1

PMID : 24470511






3 Functional Relationships(s)
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1 Phase Ib study of Buparlisib plus Trastuzumab in patients with HER2-positive advanced or metastatic breast cancer that has progressed on Trastuzumab-based therapy. NVP-BKM120 erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 The purpose of this study was to determine the clinical activity of the PI3K inhibitor buparlisib (BKM120) in patients with HER2(+) advanced/metastatic breast cancer resistant to trastuzumab-based therapy. NVP-BKM120 erb-b2 receptor tyrosine kinase 2 Homo sapiens
3 The purpose of this study was to determine the clinical activity of the PI3K inhibitor buparlisib (BKM120) in patients with HER2(+) advanced/metastatic breast cancer resistant to trastuzumab-based therapy. NVP-BKM120 erb-b2 receptor tyrosine kinase 2 Homo sapiens